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Appointment of Miriam Merad, MD, PhD, as Director of the Mount Sinai Immunology Institute

Monday, September 19, 2016   (0 Comments)
Posted by: Julie Briggs
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We are pleased to share that Miriam Merad, MD, PhD, has been appointed Director of the Mount Sinai Immunology Institute at Icahn School of Medicine at Mount Sinai (ISMMS).


Dr. Merad, the Mount Sinai Professor in Cancer Immunology, is an internationally acclaimed physician-scientist and a leader in the fields of dendritic cell and macrophage biology with a focus on their contribution to human diseases.  Her pioneering work mapping the regulatory network of dendritic cells (DCs) resulted in identification of a lineage of DC, the CD103+ DC, which is now considered a key target to improve antiviral and antitumor immunity.  Dr. Merad also discovered that, contrary to previously held beliefs that monocytes are precursors of macrophages, tissue-resident macrophages in fact arise from embryonic precursors that take residence in tissues prior to birth and are maintained independently of adult hematopoiesis. These insights are now being used to develop novel macrophage and dendritic cell-specific targets for the treatment of cancer and inflammatory diseases. 


Dr. Merad holds a joint-primary appointment in the Department of Oncological Sciences and the Department of Medicine and is also a member of the Immunology Institute and the Tisch Cancer Center.  In 2010, Dr. Merad founded the Human Immune Monitoring Core at ISMMS to study the contribution of the immune system to human diseases.  The following year, she became the program leader of the Cancer Immunology Program at The Tisch Cancer Institute, which she now co-leads with Nina Bhardwaj, MD, PhD.


After earning her MD from the University of Algiers in Algeria, Dr. Merad undertook a residency in hematology at the University of Paris and became board certified in both hematology and oncology.  Dr. Merad then earned a PhD in immunology in a collaborative program between Stanford University and the University of Paris VII.  She completed a postdoctoral fellowship in immunology at Stanford University.  Dr. Merad joined the ISMMS faculty in 2004 as Assistant Professor and was promoted to Associate Professor with tenure in 2007, to Professor in 2010, and to her endowed chair in 2014. 


Dr. Merad receives generous funding from the National Institutes of Health (NIH) for her research on innate immunity and their contribution to human disease, and belongs to several NIH consortia. She is an elected member of the American Society for Clinical Investigation, and lectures around the world on her work. 


Please join me us in congratulating Dr. Merad on her appointment as Director of the Mount Sinai Immunology Institute.


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